Are there other things which will affect the smell of my perfume? Age, diet, environment, and medication can all affect the smell of your fragrance. Related articles Can I wear a fragrance meant for the opposite sex? How do we mix or select to combine the perfume without having to smell the selections first? How do I know I'll like the scent of the "New Me" when I receive it? What are unisex / shared fragrances and why they so popular now?